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Actin filaments labeled with fluorescent phalloidin. Actin forms the major part of the cytoskeleton - the scaffolding that holds a cell in shape. Tiled view of a mature tubule with 40x lens on Zeiss 880 confocal.

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Comment by John Robinson on January 31, 2018 at 20:12

Great microscopy Ian

Comment by ian on January 24, 2018 at 15:41

Yeh in Amoeboid things actin filaments polymerise ( gel ) at the leading edge extending the cell  and break down at the trailing end ( sol ) contracting it in. In this view we're seeing the stable scaffold of an area that's not thinking of moving. In the other pic we've got actin filaments extending out as the cell starts to move

Comment by Jan-Maarten Luursema on January 24, 2018 at 10:34

Awesome! Are these fibers involved in locomotion; do they contract?

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